Epigenetics and depressive disorders: a review of current progress and future directions.
Identifieur interne : 002E46 ( Main/Exploration ); précédent : 002E45; suivant : 002E47Epigenetics and depressive disorders: a review of current progress and future directions.
Auteurs : Vania Januar [Australie] ; Richard Saffery [Australie] ; Joanne Ryan [Australie]Source :
- International journal of epidemiology [ 1464-3685 ] ; 2015.
Descripteurs français
- KwdFr :
- Animaux, Dépression (génétique), Facteur neurotrophique dérivé du cerveau (génétique), Humains, Interaction entre gènes et environnement, Marqueurs biologiques (analyse), Modèles animaux de maladie humaine, Méthylation de l'ADN, Récepteurs aux glucocorticoïdes (génétique), Transporteurs de la sérotonine (génétique), Trouble dépressif majeur (génétique), Épigenèse génétique.
- MESH :
- analyse : Marqueurs biologiques.
- génétique : Dépression, Facteur neurotrophique dérivé du cerveau, Récepteurs aux glucocorticoïdes, Transporteurs de la sérotonine, Trouble dépressif majeur.
- Animaux, Humains, Interaction entre gènes et environnement, Modèles animaux de maladie humaine, Méthylation de l'ADN, Épigenèse génétique.
English descriptors
- KwdEn :
- Animals, Biomarkers (analysis), Brain-Derived Neurotrophic Factor (genetics), DNA Methylation, Depression (genetics), Depressive Disorder, Major (genetics), Disease Models, Animal, Epigenesis, Genetic, Gene-Environment Interaction, Humans, Receptors, Glucocorticoid (genetics), Serotonin Plasma Membrane Transport Proteins (genetics).
- MESH :
- chemical , analysis : Biomarkers.
- chemical , genetics : Brain-Derived Neurotrophic Factor, Receptors, Glucocorticoid, Serotonin Plasma Membrane Transport Proteins.
- genetics : Depression, Depressive Disorder, Major.
- Animals, DNA Methylation, Disease Models, Animal, Epigenesis, Genetic, Gene-Environment Interaction, Humans.
Abstract
Several broad lines of evidence support the involvement of epigenetic processes in neurodevelopment and psychiatric disorders. Epigenetic disruption also provides a potential mechanism to account for the numerous gene-environment interactions that have been reported in association with neuropsychiatric phenotypes.
DOI: 10.1093/ije/dyu273
PubMed: 25716985
Affiliations:
- Australie
- Languedoc-Roussillon, Occitanie (région administrative), Victoria (État)
- Melbourne, Montpellier
- Université de Melbourne
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Le document en format XML
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type="abstract" xml:lang="en">Several broad lines of evidence support the involvement of epigenetic processes in neurodevelopment and psychiatric disorders. 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